Under what conditions may public-private partnerships (PPPs or P3s) involved in multilateral development policy advance public interest goals in global intellectual property (IP)? This paper attempts to assess how non-profit partners within certain development policy PPPs generate and/or implement norms, thereby impacting public policies promoting both innovations as well as access to those innovations. As hybrid actors operating across polyglot transnational networks, the practices of these PPPs illuminate and deepen both the global governance and the IP literatures. They reveal PPPs as regime-straddlers linking the legal domains of trade and IP to those of development.